Myocd - myocardin Gene

Also Known as Mycd

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246297

Summary

Predicted to enable several functions, including R-SMAD binding activity; enzyme binding activity; and transcription coactivator activity. Involved in several processes, including hepatic stellate cell activation; positive regulation of cell differentiation; and positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation. Predicted to be located in chromatin. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in congenital megabladder. Orthologous to human MYOCD (myocardin). [provided by Alliance of Genome Resources, Apr 2022]

Myocd Products (2)

mRNA Protein Name
NM_001414232.1 NP_001401161.1 myocardin isoform 1
NM_182667.3 NP_872608.1 myocardin isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16054032 RGD
Biological Process GO Annotation Evidence References Source
involved in cardiac vascular smooth muscle cell differentiation IDA
IDA: Inferred from direct assay
16151017 RGD
involved in cell growth involved in cardiac muscle cell development IMP
IMP: Inferred from mutant phenotype
18772130 RGD
involved in cellular response to angiotensin IEP
IEP: Inferred from expression pattern
15016729 RGD
involved in cellular response to growth factor stimulus IEP
IEP: Inferred from expression pattern
20621093 RGD
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
20621093 RGD
involved in hepatic stellate cell activation IMP
IMP: Inferred from mutant phenotype
19793196 RGD
involved in positive regulation of epithelial to mesenchymal transition IMP
IMP: Inferred from mutant phenotype
23270756 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12392995 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
19237536 RGD
involved in positive regulation of vascular associated smooth muscle cell migration IMP
IMP: Inferred from mutant phenotype
23855625 RGD
involved in regulation of smooth muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
12756293 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
23855625 RGD
involved in response to muscle stretch IEP
IEP: Inferred from expression pattern
23855625 RGD
involved in smooth muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
12392995 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
19237536 RGD
located in nucleus IDA
IDA: Inferred from direct assay
19237536 RGD
part of protein-DNA complex IDA
IDA: Inferred from direct assay
15016729 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myocardin

  • transcription factor myocardin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08955 MYOCD Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myocd NCBI NCBI:93649