2. Gene
  3. Prph - peripherin Gene

Prph - peripherin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Perf; Prph1

Gene ID: 24688 | Gene type: protein coding

About Prph

Summary

Predicted to enable structural molecule activity. Involved in intermediate filament Cytoskeleton organization. Located in neuronal cell body; terminal bouton; and type III intermediate filament. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 1. Orthologous to human PRPH (peripherin). [provided by Alliance of Genome Resources, Apr 2022]

Prph Products(1)

mRNA Protein Name
NM_012633.3 NP_036765.3 peripherin
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
9971739 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
9388258 RGD
Biological Process GO Annotation Evidence Reference Source
involved in intermediate filament cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
8575457 RGD
Cellular Component GO Annotation Evidence Reference Source
located in neuronal cell body IDA
IDA: Inferred from direct assay
8616889 RGD
located in terminal bouton IDA
IDA: Inferred from direct assay
10416873 RGD
located in type III intermediate filament IDA
IDA: Inferred from direct assay
2624740 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peripherin

peripherin 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11217 PRPH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11218 PRPH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prph NCBI NCBI:5630