Klk1c2 - kallikrein 1-related peptidase C2 Gene

Rattus norvegicus

Also known as Ton; KLK2; Klna1; rGK-2

Gene ID: 24841 | Gene type: protein coding

About Klk1c2

Summary

Enables serine-type peptidase activity. Predicted to be involved in regulation of systemic arterial blood pressure and zymogen activation. Predicted to be active in secretory granule. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to human KLK1 (Kallikrein 1). [provided by Alliance of Genome Resources, Apr 2022]

Klk1c2 Products(1)

mRNA	Protein	Name
NM_012677.1	NP_036809.1	tonin precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables serine-type peptidase activity	IDA IDA: Inferred from direct assay	2550051	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tonin

RSKG-5	S2 kallikrein
esterase 1	glandular kallikrein-2
kallikrein a1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07376	KLK12 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

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