Klk1c2 - kallikrein 1-related peptidase C2 Gene

Also Known as Ton; KLK2; Klna1; rGK-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24841

Summary

Enables serine-type peptidase activity. Predicted to be involved in regulation of systemic arterial blood pressure and zymogen activation. Predicted to be active in secretory granule. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to human KLK1 (Kallikrein 1). [provided by Alliance of Genome Resources, Apr 2022]

Klk1c2 Products (1)

mRNA Protein Name
NM_012677.1 NP_036809.1 tonin precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables serine-type peptidase activity IDA
IDA: Inferred from direct assay
2550051 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tonin

  • RSKG-5

  • S2 kallikrein

  • esterase 1

  • glandular kallikrein-2

  • kallikrein a1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07376 KLK12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown