Umod - uromodulin Gene

Also Known as THP

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25128

Summary

Predicted to enable IgG binding activity. Predicted to be an extracellular matrix structural constituent. Involved in response to organic substance. Located in several cellular components, including Golgi apparatus; apical part of cell; and membrane raft. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Orthologous to human UMOD (uromodulin). [provided by Alliance of Genome Resources, Apr 2022]

Umod Products (1)

mRNA Protein Name
NM_017082.2 NP_058778.2 uromodulin precursor
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18830570 RGD
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
3910623 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
16807540 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uromodulin

  • Urmodulin (Tamm-Horsfall protein)

  • tamm-Horsfall urinary glycoprotein

Orthologs Information

Species Symbol Source ID
Homo sapiens Umod NCBI NCBI:7369