Lyz2 - lysozyme 2 Gene

Also Known as Lyz; Lysz; Lyz1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25211

Summary

Enables lysozyme activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Located in several cellular components, including Golgi cis cisterna; cytoplasmic vesicle; and rough endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in familial visceral amyloidosis. Orthologous to human LYZ (lysozyme). [provided by Alliance of Genome Resources, Apr 2022]

Lyz2 Products (1)

mRNA Protein Name
NM_012771.3 NP_036903.2 lysozyme C-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables hydrolase activity, acting on glycosyl bonds IMP
IMP: Inferred from mutant phenotype
2840982 RGD
enables lysozyme activity IDA
IDA: Inferred from direct assay
12965127 RGD
enables lysozyme activity IMP
IMP: Inferred from mutant phenotype
2840982 RGD
Biological Process GO Annotation Evidence References Source
involved in defense response to Gram-negative bacterium IMP
IMP: Inferred from mutant phenotype
2840982 RGD
involved in defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
2840982 RGD
Cellular Component GO Annotation Evidence References Source
located in Golgi cis cisterna IDA
IDA: Inferred from direct assay
9208328 RGD
located in Golgi stack IDA
IDA: Inferred from direct assay
9208328 RGD
located in endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
9208328 RGD
located in microvillus IDA
IDA: Inferred from direct assay
9208328 RGD
located in rough endoplasmic reticulum lumen IDA
IDA: Inferred from direct assay
9208328 RGD
located in secretory granule IDA
IDA: Inferred from direct assay
9208328 RGD
located in trans-Golgi network transport vesicle IDA
IDA: Inferred from direct assay
9208328 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysozyme C-1

  • 1,4-beta-N-acetylmuramidase C