2. Gene
  3. Nup153 - nucleoporin 153 Gene

Nup153 - nucleoporin 153 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as NUCZINK

Gene ID: 25281 | Gene type: protein coding

About Nup153

Summary

Enables several functions, including nuclear localization sequence binding activity; small GTPase binding activity; and zinc ion binding activity. Involved in mitotic cell cycle. Located in annulate lamellae and nucleus. Part of nuclear pore nuclear basket. Orthologous to human NUP153 (nucleoporin 153). [provided by Alliance of Genome Resources, Apr 2022]

Nup153 Products(1)

mRNA Protein Name
NM_001100470.1 NP_001093940.1 nuclear pore complex protein Nup153
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
10362555 RGD
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
8422679 RGD
enables nuclear localization sequence binding IDA
IDA: Inferred from direct assay
7878057 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9531546 RGD
enables small GTPase binding IPI
IPI: Inferred from physical interaction
19505478 RGD
enables zinc ion binding IDA
IDA: Inferred from direct assay
19505478 RGD
Cellular Component GO Annotation Evidence Reference Source
located in annulate lamellae IDA
IDA: Inferred from direct assay
8832404 RGD
located in nuclear inclusion body IDA
IDA: Inferred from direct assay
11839768 RGD
located in nuclear membrane IDA
IDA: Inferred from direct assay
11839768 RGD
located in nuclear periphery IDA
IDA: Inferred from direct assay
11839768 RGD
part of nuclear pore IDA
IDA: Inferred from direct assay
15703211 RGD
part of nuclear pore nuclear basket IDA
IDA: Inferred from direct assay
11839768 RGD
located in nucleoplasmic side of nuclear pore IDA
IDA: Inferred from direct assay
8422679 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
19505478 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear pore complex protein Nup153

153 kDa nucleoporin

nucleoporin 153kD

nucleoporin Nup153

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120072 PF-3450074 Inhibitor 98.89% Unkown
HY-RS09685 NUP153 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nup153 NCBI NCBI:9972