Utrn - utrophin Gene

Also Known as DRP-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25600

Summary

Enables actin filament binding activity. Involved in neuromuscular junction development and response to denervation involved in regulation of muscle adaptation. Located in cortical actin cytoskeleton; growth cone; and neuromuscular junction. Orthologous to human UTRN (utrophin). [provided by Alliance of Genome Resources, Apr 2022]

Utrn Products (1)

mRNA Protein Name
NM_013070.2 NP_037202.2 utrophin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin filament binding IDA
IDA: Inferred from direct assay
12742015 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10545507 RGD
Biological Process GO Annotation Evidence References Source
involved in neuromuscular junction development IDA
IDA: Inferred from direct assay
9604203 RGD
involved in response to denervation involved in regulation of muscle adaptation IEP
IEP: Inferred from expression pattern
8906620 RGD
Cellular Component GO Annotation Evidence References Source
located in cortical actin cytoskeleton IDA
IDA: Inferred from direct assay
10760950 RGD
located in growth cone IDA
IDA: Inferred from direct assay
10923681 RGD
located in neuromuscular junction IDA
IDA: Inferred from direct assay
9604203 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

utrophin

  • dystrophin-related protein 1

  • utrophin (homologous to dystrophin)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15582 UTRN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Utrn NCBI NCBI:7402