mt-Cytb - cytochrome b, mitochondrial Gene

Also Known as CYTB

Species: Rattus norvegicus (strain: BN/SsNHsdMCW)

Gene Type: protein coding
Gene ID: 26192

Summary

Predicted to enable ubiquinol-cytochrome-c reductase activity. Involved in several processes, including electron transport coupled proton transport; response to cobalamin; and response to glucagon. Located in mitochondrial inner membrane. Is integral component of mitochondrial inner membrane. Part of protein-containing complex. Biomarker of thyrotoxicosis; type 2 diabetes mellitus; and visual epilepsy. Human ortholog(s) of this gene implicated in ovarian carcinoma and urinary bladder Cancer. Orthologous to human MT-CYB (mitochondrially encoded cytochrome b). [provided by Alliance of Genome Resources, Apr 2022]

mt-Cytb Products (2)

mRNA Protein Name
YP_665641.1 cytochrome b (mitochondrion) [Rattus norvegicus]
YP_665641.1 cytochrome b (mitochondrion) [Rattus norvegicus]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
6263624 RGD
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
9501001 RGD
involved in electron transport coupled proton transport IMP
IMP: Inferred from mutant phenotype
6293466 RGD
involved in response to cadmium ion IDA
IDA: Inferred from direct assay
8269544 RGD
involved in response to calcium ion IDA
IDA: Inferred from direct assay
2313294 RGD
involved in response to cobalamin IEP
IEP: Inferred from expression pattern
7508436 RGD
involved in response to copper ion IEP
IEP: Inferred from expression pattern
10535524 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
6263903 RGD
involved in response to glucagon IDA
IDA: Inferred from direct assay
6322776 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
6215275 RGD
involved in response to hyperoxia IEP
IEP: Inferred from expression pattern
18481000 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
8333494 RGD
involved in response to mercury ion IMP
IMP: Inferred from mutant phenotype
8512585 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
5954822 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
15207643 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
7482592 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
8838689 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
6263624 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
6263624 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

  • cytochrome b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08761 MT-CYB Human Pre-designed siRNA Set A Pre-designed Set / Unkown