mt-Cytb - cytochrome b, mitochondrial Gene

Rattus norvegicus (strain: BN/SsNHsdMCW)

Also known as CYTB

Gene ID: 26192 | Gene type: protein coding

About mt-Cytb

Summary

Predicted to enable ubiquinol-cytochrome-c reductase activity. Involved in several processes, including electron transport coupled proton transport; response to cobalamin; and response to glucagon. Located in mitochondrial inner membrane. Is integral component of mitochondrial inner membrane. Part of protein-containing complex. Biomarker of thyrotoxicosis; type 2 diabetes mellitus; and visual epilepsy. Human ortholog(s) of this gene implicated in ovarian carcinoma and urinary bladder Cancer. Orthologous to human MT-CYB (mitochondrially encoded cytochrome b). [provided by Alliance of Genome Resources, Apr 2022]

mt-Cytb Products(2)

mRNA	Protein	Name
YP_665641.1 cytochrome b (mitochondrion) [Rattus norvegicus]
YP_665641.1		cytochrome b (mitochondrion) [Rattus norvegicus]

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	6263624	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in animal organ regeneration	IEP IEP: Inferred from expression pattern	9501001	RGD
involved in electron transport coupled proton transport	IMP IMP: Inferred from mutant phenotype	6293466	RGD
involved in response to cadmium ion	IDA IDA: Inferred from direct assay	8269544	RGD
involved in response to calcium ion	IDA IDA: Inferred from direct assay	2313294	RGD
involved in response to cobalamin	IEP IEP: Inferred from expression pattern	7508436	RGD
involved in response to copper ion	IEP IEP: Inferred from expression pattern	10535524	RGD
involved in response to ethanol	IEP IEP: Inferred from expression pattern	6263903	RGD
involved in response to glucagon	IDA IDA: Inferred from direct assay	6322776	RGD
involved in response to hormone	IEP IEP: Inferred from expression pattern	6215275	RGD
involved in response to hyperoxia	IEP IEP: Inferred from expression pattern	18481000	RGD
involved in response to hypoxia	IEP IEP: Inferred from expression pattern	8333494	RGD
involved in response to mercury ion	IMP IMP: Inferred from mutant phenotype	8512585	RGD
involved in response to nutrient	IEP IEP: Inferred from expression pattern	5954822	RGD
involved in response to organic cyclic compound	IEP IEP: Inferred from expression pattern	15207643	RGD
involved in response to toxic substance	IEP IEP: Inferred from expression pattern	7482592	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	8838689	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in mitochondrial inner membrane	IDA IDA: Inferred from direct assay	6263624	RGD
part of protein-containing complex	IDA IDA: Inferred from direct assay	6263624	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cytochrome b

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08761	MT-CYB Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

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