mt-Co1 - cytochrome c oxidase I, mitochondrial Gene

Also Known as COI; COX1

Species: Rattus norvegicus (strain: BN/SsNHsdMCW)

Gene Type: protein coding
Gene ID: 26195

Summary

Predicted to enable heme binding activity and metal ion binding activity. Predicted to contribute to cytochrome-c oxidase activity. Involved in several processes, including cerebellum development; response to copper ion; and response to electrical stimulus. Located in mitochondrion. Used to study hepatocellular carcinoma. Biomarker of Parkinsonism. Orthologous to human MT-CO1 (mitochondrially encoded cytochrome c oxidase I). [provided by Alliance of Genome Resources, Apr 2022]

mt-Co1 Products (1)

mRNA Protein Name
YP_665631.1 cytochrome c oxidase subunit I (mitochondrion) [Rattus norvegicus]

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cerebellum development IEP
IEP: Inferred from expression pattern
2465379 RGD
involved in response to copper ion IEP
IEP: Inferred from expression pattern
18567746 RGD
involved in response to electrical stimulus IEP
IEP: Inferred from expression pattern
14519661 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
33310031 RGD
involved in response to oxidative stress IDA
IDA: Inferred from direct assay
17870132 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome c oxidase subunit 1

  • cytochrome c oxidase subunit I

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16308 mt-Co1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08757 MT-CO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-131453 Mitochondrial respiration-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Co1 NCBI NCBI:4512