mt-Nd3 - NADH dehydrogenase 3, mitochondrial Gene
Also Known as ND3
Species: Rattus norvegicus (strain: BN/SsNHsdMCW)
Summary
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Involved in cellular response to glucocorticoid stimulus; response to light intensity; and response to oxidative stress. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Used to study Huntington's disease and Parkinson's disease. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and Parkinson's disease. Orthologous to human MT-ND3 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
mt-Nd3 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| YP_665636.1 NADH dehydrogenase subunit 3 (mitochondrion) [Rattus norvegicus] | ||
| YP_665636.1 | NADH dehydrogenase subunit 3 (mitochondrion) [Rattus norvegicus] |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cellular response to glucocorticoid stimulus |
IDA
IDA: Inferred from direct assay
|
21368868 | RGD |
| involved in response to hormone |
IMP
IMP: Inferred from mutant phenotype
|
7763274 | RGD |
| involved in response to light intensity |
IEP
IEP: Inferred from expression pattern
|
15277468 | RGD |
| involved in response to oxidative stress |
IDA
IDA: Inferred from direct assay
|
17870132 | RGD |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS08798 | MT-ND3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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