2. Gene
  3. mt-Nd3 - NADH dehydrogenase 3, mitochondrial Gene

mt-Nd3 - NADH dehydrogenase 3, mitochondrial Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus (strain: BN/SsNHsdMCW)

Also known as ND3

Gene ID: 26199 | Gene type: protein coding

About mt-Nd3

Summary

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Involved in cellular response to glucocorticoid stimulus; response to light intensity; and response to oxidative stress. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial respiratory chain complex I. Used to study Huntington's disease and Parkinson's disease. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and Parkinson's disease. Orthologous to human MT-ND3 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd3 Products(2)

mRNA Protein Name
YP_665636.1 NADH dehydrogenase subunit 3 (mitochondrion) [Rattus norvegicus]
YP_665636.1 NADH dehydrogenase subunit 3 (mitochondrion) [Rattus norvegicus]
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to glucocorticoid stimulus IDA
IDA: Inferred from direct assay
21368868 RGD
involved in response to hormone IMP
IMP: Inferred from mutant phenotype
7763274 RGD
involved in response to light intensity IEP
IEP: Inferred from expression pattern
15277468 RGD
involved in response to oxidative stress IDA
IDA: Inferred from direct assay
17870132 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase subunit 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08798 MT-ND3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Nd3 NCBI NCBI:4537