GBX1 - gastrulation brain homeobox 1 Gene
Also Known as Huh-17
Species: Homo sapiens
About GBX1
This gene has 2 transcripts (splice variants), 188 orthologues and 1 paralogue. Restricted expression toward testis (RPKM 2.3).
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of nervous system development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within adult walking behavior; neuron differentiation; and proprioception. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
GBX1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001098834.3 | NP_001092304.1 | homeobox protein GBX-1 |
GBX1 Protein Structure
Homeobox: Homeobox domain (262 - 318)
- 0
- 100
- 200
- 300
- 363 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
homeobox protein GBX-1 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Currarino Syndrome |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS05314 | GBX1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | GBX1 | VGNC | VGNC:108408 |
| Bos taurus | GBX1 | VGNC | VGNC:53645 |
| Mus musculus | GBX1 | MGD | MGI:95667 |
| Felis catus | GBX1 | VGNC | VGNC:62484 |
| Rattus norvegicus | GBX1 | RGD | RGD:621864 |
| Others | GBX1 | NCBI |
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