2. Gene
  3. Orc4 - origin recognition complex, subunit 4 Gene

Orc4 - origin recognition complex, subunit 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Orc4P; Orc4l; mMmORC4

Gene ID: 26428 | Gene type: protein coding

About Orc4

Summary

Predicted to enable DNA replication origin binding activity and nucleotide binding activity. Predicted to be involved in DNA replication initiation. Predicted to act upstream of or within DNA replication. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of nuclear origin of replication recognition complex. Predicted to colocalize with chromosome, telomeric region. Is expressed in brain; embryo; and pancreas epithelium. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 2. Orthologous to human ORC4 (origin recognition complex subunit 4). [provided by Alliance of Genome Resources, Apr 2022]

Orc4 Products(3)

mRNA Protein Name
NM_001177313.1 NP_001170784.1 origin recognition complex subunit 4 isoform 2
NM_001355296.1 NP_001342225.1 origin recognition complex subunit 4 isoform 1
NM_011958.4 NP_036088.3 origin recognition complex subunit 4 isoform 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within DNA replication IMP
IMP: Inferred from mutant phenotype
34977916 MGI
involved in polar body extrusion after meiotic divisions IMP
IMP: Inferred from mutant phenotype
28230328 MGI
involved in protein polymerization IDA
IDA: Inferred from direct assay
28230328 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytoplasm IDA
IDA: Inferred from direct assay
28230328 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

origin recognition complex subunit 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-180157 CDK2-IN-51 Inhibitor / Unkown
HY-RS09828 ORC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Orc4 NCBI NCBI:5000