2. Gene
  3. Eme1 - essential meiotic structure-specific endonuclease 1 Gene

Eme1 - essential meiotic structure-specific endonuclease 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 6820428D13

Gene ID: 268465 | Gene type: protein coding

About Eme1

Summary

Predicted to enable DNA binding activity; Endonuclease activity; and metal ion binding activity. Predicted to be involved in DNA metabolic process and mitotic intra-S DNA damage checkpoint signaling. Predicted to act upstream of or within response to intra-S DNA damage checkpoint signaling. Located in heterochromatin. Is expressed in several structures, including adrenal medulla; respiratory system; sensory organ; skeleton; and trunk mesenchyme derived from neural crest. Orthologous to human EME1 (essential meiotic structure-specific Endonuclease 1). [provided by Alliance of Genome Resources, Apr 2022]

Eme1 Products(2)

mRNA Protein Name
NM_001379688.1 NP_001366617.1 crossover junction endonuclease EME1 isoform 1
NM_177752.5 NP_808420.1 crossover junction endonuclease EME1 isoform 2
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18692478 MGI
Cellular Component GO Annotation Evidence Reference Source
located in chromatin IDA
IDA: Inferred from direct assay
18692478 MGI
located in heterochromatin IDA
IDA: Inferred from direct assay
18692478 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

crossover junction endonuclease EME1

essential meiotic endonuclease 1 homolog 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-181840 MU262 Inhibitor / Unkown
HY-RS04346 EME1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eme1 NCBI NCBI:146956