Med14 - mediator complex subunit 14 Gene

Mus musculus

Also known as ORF1; Crsp2; Gm641; Trap170; 9930001L01Rik

Gene ID: 26896 | Gene type: protein coding

About Med14

Summary

Predicted to enable transcription coactivator activity. Acts upstream of or within stem cell population maintenance. Part of mediator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human MED14 (mediator complex subunit 14). [provided by Alliance of Genome Resources, Apr 2022]

Med14 Products(2)

mRNA	Protein	Name
NM_001048208.1	NP_001041673.1	mediator of RNA polymerase II transcription subunit 14 isoform a
NM_012005.3	NP_036135.3	mediator of RNA polymerase II transcription subunit 14 isoform b

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within somatic stem cell population maintenance	IMP IMP: Inferred from mutant phenotype	20720539	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of mediator complex	IDA IDA: Inferred from direct assay	15340084	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

mediator of RNA polymerase II transcription subunit 14

CRSP complex subunit 2	cofactor required for Sp1 transcriptional activation subunit 2 (150 kDa)
cofactor required for Sp1 transcriptional activation, subunit 2	thyroid hormone receptor-associated protein complex 170 kDa component

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08285	MED14 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Med14	NCBI	NCBI:9282

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