Fbxl4 - F-box and leucine-rich repeat protein 4 Gene

Also Known as FBL4; FBL5

Species: Mus musculus

Gene Type: protein coding
Gene ID: 269514

Summary

Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in mitochondrial intermembrane space and nuclear speck. Predicted to be part of SCF ubiquitin Ligase complex. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 13. Orthologous to human FBXL4 (F-box and leucine rich repeat protein 4). [provided by Alliance of Genome Resources, Apr 2022]

Fbxl4 Products (1)

mRNA Protein Name
NM_172988.4 NP_766576.1 F-box/LRR-repeat protein 4

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within autophagy of mitochondrion IMP
IMP: Inferred from mutant phenotype
32525278 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

F-box/LRR-repeat protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04792 FBXL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fbxl4 NCBI NCBI:26235