2. Gene
  3. Tspan12 - tetraspanin 12 Gene

Tspan12 - tetraspanin 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tm4sf12; 9030619E17

Gene ID: 269831 | Gene type: protein coding

About Tspan12

Summary

Involved in cell surface receptor signaling pathway; regulation of angiogenesis; and retina layer formation. Is integral component of plasma membrane. Is expressed in genitourinary system. Used to study exudative vitreoretinopathy. Human ortholog(s) of this gene implicated in exudative vitreoretinopathy 5. Orthologous to human TSPAN12 (tetraspanin 12). [provided by Alliance of Genome Resources, Apr 2022]

Tspan12 Products(7)

mRNA Protein Name
NM_001363814.1 NP_001350743.1 tetraspanin-12 isoform 2
NM_001411747.1 NP_001398676.1 tetraspanin-12 isoform 1
NM_001411748.1 NP_001398677.1 tetraspanin-12 isoform 1
NM_001411749.1 NP_001398678.1 tetraspanin-12 isoform 1
NM_001411750.1 NP_001398679.1 tetraspanin-12 isoform 1
NM_001411751.1 NP_001398680.1 tetraspanin-12 isoform 3
NM_173007.4 NP_766595.1 tetraspanin-12 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
NOT enables Wnt receptor activity IDA
IDA: Inferred from direct assay
19837033 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within Norrin signaling pathway IMP
IMP: Inferred from mutant phenotype
30478038 MGI
involved in cell surface receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
19837033 MGI
acts upstream of or within maintenance of blood-brain barrier IMP
IMP: Inferred from mutant phenotype
30478038 MGI
involved in regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
19837033 MGI
involved in retina layer formation IMP
IMP: Inferred from mutant phenotype
19837033 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
19837033 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tetraspanin-12

transmembrane 4 superfamily member 12

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15160 TSPAN12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tspan12 NCBI NCBI:23554