2. Gene
  3. Mbtps2 - membrane-bound transcription factor peptidase, site 2 Gene

Mbtps2 - membrane-bound transcription factor peptidase, site 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 9630032G22Rik

Gene ID: 270669 | Gene type: protein coding

About Mbtps2

Summary

Predicted to enable metalloendopeptidase activity. Predicted to be involved in several processes, including bone maturation; membrane protein intracellular domain proteolysis; and regulation of transcription, DNA-templated. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in X-linked keratosis follicularis spinulosa decalvans; X-linked mutilating palmoplantar keratoderma with periorificial keratotic plaques; ichthyosis follicularis-alopecia-photophobia syndrome 1; and osteogenesis imperfecta type 19. Orthologous to human MBTPS2 (membrane bound transcription factor peptidase, site 2). [provided by Alliance of Genome Resources, Apr 2022]

Mbtps2 Products(1)

mRNA Protein Name
NM_172307.3 NP_758511.1 membrane-bound transcription factor site-2 protease
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in mitotic G2 DNA damage checkpoint signaling IDA
IDA: Inferred from direct assay
37178686 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

membrane-bound transcription factor site-2 protease

S2P endopeptidase

endopeptidase S2P

membrane-bound transcription factor protease, site 2

site-2 protease

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08199 MBTPS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mbtps2 NCBI NCBI:51360