Mbtps2 - membrane-bound transcription factor peptidase, site 2 Gene

Also Known as 9630032G22Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 270669

Summary

Predicted to enable metalloendopeptidase activity. Predicted to be involved in several processes, including bone maturation; membrane protein intracellular domain proteolysis; and regulation of transcription, DNA-templated. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; liver; and lung. Human ortholog(s) of this gene implicated in X-linked keratosis follicularis spinulosa decalvans; X-linked mutilating palmoplantar keratoderma with periorificial keratotic plaques; ichthyosis follicularis-alopecia-photophobia syndrome 1; and osteogenesis imperfecta type 19. Orthologous to human MBTPS2 (membrane bound transcription factor peptidase, site 2). [provided by Alliance of Genome Resources, Apr 2022]

Mbtps2 Products (1)

mRNA Protein Name
NM_172307.3 NP_758511.1 membrane-bound transcription factor site-2 protease

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence 参考文献 由来
involved in mitotic G2 DNA damage checkpoint signaling IDA
IDA: Inferred from direct assay
37178686 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

membrane-bound transcription factor site-2 protease

  • S2P endopeptidase

  • endopeptidase S2P

  • membrane-bound transcription factor protease, site 2

  • site-2 protease

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS08199 MBTPS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Mbtps2 NCBI NCBI:51360