GK2 - glycerol kinase 2 Gene

Also Known as GKP2; GKTA

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2712

About GK2

Cytogenetic location: 4q21.21 Genomic coordinates (GRCh38): 4:79,406,361-79,408,228 (from NCBI)

This gene has 1 transcript (splice variant), 246 orthologues and 6 paralogues.

Summary

Predicted to enable glycerol kinase activity. Predicted to be involved in several processes, including glycerol metabolic process; glycerol-3-phosphate biosynthetic process; and triglyceride metabolic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

GK2 Products (1)

mRNA Protein Name
NM_033214.3 NP_149991.2 glycerol kinase 2

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
28852571 GOA
Cellular Component GO Annotation Evidence Références Source
located in sperm midpiece IDA
IDA: Inferred from direct assay
28852571 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GK2 Protein Structure

FGGY_N

FGGY_N: FGGY family of carbohydrate kinases, N-terminal domain (14 - 266)

FGGY_C

FGGY_C: FGGY family of carbohydrate kinases, C-terminal domain (275 - 466)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 553 a.a.
Protein Preferred Names Protein Names

glycerol kinase 2

  • ATP:glycerol 3-phosphotransferase 2

Related Diseases

Diseases Alias
Glycerol Kinase Deficiency

  • Hyperglycerolemia

  • GKD

  • Gk Deficiency

  • Gk1 Deficiency

  • Deficiency Of Glycerol Kinase

  • Isolated Glycerol Kinase Deficiency

  • Glycerol Kinase Deficiency, Adult Form

  • Glycerol Kinase Deficiency, Juvenile Form

  • Deficiency, Glycerol Kinase
Hypoadrenocorticism, Familial

  • Addison Disease

  • Primary Adrenocortical Insufficiency

  • Addison'S Disease

  • Adrenal Gland Hypofunction

  • Adrenal Hypoplasia

  • Adrenal Aplasia

  • Addison Disease, Chronic Adrenal Insufficiency

  • Primary Hypoadrenalism

  • Hypoadrenocorticism Familial

  • Autoimmune Addison Disease

  • Autoimmune Adrenalitis

  • Classic Addison Disease

  • Primary Addison Disease

  • Addisons Disease

  • Addison Disease, Susceptibility To

  • Autoimmune Primary Adrenal Insufficiency

  • Addison'S Disease Due To Autoimmunity
Muscular Dystrophy, Duchenne Type

  • Duchenne Muscular Dystrophy

  • DMD

  • Muscular Dystrophy, Duchenne

  • Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type

  • Severe Dystrophinopathy, Duchenne Type

  • Muscular Dystrophy Duchenne

  • Dystrophy, Muscular, Duchenne Type

  • Benign Duchenne Muscular Dystrophy

  • Duchenne Motor Neuron Disease

  • Duchenne Type Dystrophy

  • Duchenne-Griesinger Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-154802 TCO-GK-PEG4-NHS ester / Unkown
HY-RS05244 GALK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05458 GK2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17868 Gk2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20025 Galk2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24337 Gk2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GK2 VGNC VGNC:57407
Rattus norvegicus GK2 RGD RGD:1303263
Mus musculus GK2 MGD MGI:1329027
Macaca mulatta GK2 VGNC VGNC:106585
Others GK2 NCBI