Rhbdd3 - rhomboid domain containing 3 Gene

Also Known as Ptag

Species: Mus musculus

Gene Type: protein coding
Gene ID: 279766

Summary

Predicted to enable serine-type endopeptidase activity. Acts upstream of or within several processes, including liver development; negative regulation of natural killer cell activation; and positive regulation of protein catabolic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human RHBDD3 (rhomboid domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Rhbdd3 Products (4)

mRNA Protein Name
NM_001290491.1 NP_001277420.1 rhomboid domain-containing protein 3 isoform b
NM_001290492.1 NP_001277421.1 rhomboid domain-containing protein 3 isoform a
NM_001290493.1 NP_001277422.1 rhomboid domain-containing protein 3 isoform a
NM_177370.4 NP_796344.1 rhomboid domain-containing protein 3 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23610400 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within MAPK cascade IDA
IDA: Inferred from direct assay
23610400 MGI
acts upstream of or within liver development IMP
IMP: Inferred from mutant phenotype
23610400 MGI
acts upstream of or within negative regulation of natural killer cell activation IMP
IMP: Inferred from mutant phenotype
23610400 MGI
acts upstream of or within positive regulation of protein catabolic process IDA
IDA: Inferred from direct assay
23610400 MGI
acts upstream of or within regulation of acute inflammatory response IMP
IMP: Inferred from mutant phenotype
23610400 MGI
acts upstream of or within regulation of protein secretion IMP
IMP: Inferred from mutant phenotype
23610400 MGI
acts upstream of or within response to xenobiotic stimulus IMP
IMP: Inferred from mutant phenotype
23610400 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rhomboid domain-containing protein 3

  • pituitary-derived proapoptotic

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11933 RHBDD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rhbdd3 NCBI NCBI:25807