AQP11 - aquaporin 11 Gene

Homo sapiens

Also known as AQPX1

Gene ID: 282679 | Gene type: protein coding

About AQP11

Cytogenetic location: 11q14.1 Genomic coordinates (GRCh38): 11:77,589,953-77,610,356 (from NCBI)

This gene has 2 transcripts (splice variants), 246 orthologues and 2 paralogues. Biased expression in duodenum (RPKM 12.3), small intestine (RPKM 11.2) and 11 other tissues.

Summary

Enables glycerol channel activity and water channel activity. Involved in several processes, including glycerol transport; hydrogen peroxide transmembrane transport; and protein homooligomerization. Located in cell surface; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

AQP11 Products(2)

mRNA	Protein	Name
NM_001363477.2	NP_001350406.1	aquaporin-11 isoform 2
NM_173039.3	NP_766627.1	aquaporin-11 isoform 1

AQP11 Protein Structure

MIP

0
100
200
271 a.a.

Protein Preferred Names

Protein Names

aquaporin-11

AQP-11

Related Diseases

Diseases

Alias

Nephrogenic Diabetes Insipidus

Vasopressin-Resistant Diabetes Insipidus	Diabetes Insipidus, Nephrogenic
Diabetes Insipidus Nephrogenic	Congenital Nephrogenic Diabetes Insipidus
Adh Resistant Diabetes Insipidus	Diabetes Insipidus Nephrogenic X-Linked
Diabetes Insipidus Nephrogenic Type 1	Adh-Resistant Diabetes Insipidus
Diabetes Insipidus Renalis	Ndi
Renal Diabetes Insipidus	Familial Nephrogenic Diabetes
Antidiuretic-Hormone-Resistant Diabetes Insipidus	Adiuretin-Resistant Diabetes Insipidus
Ndi - [Nephrogenic Diabetes Insipidus]	Diabetes Tenuifluus
Adh - [Antidiuretic-Hormone] Resistant Diabetes Insipidus	Hereditary Nephrogenic Diabetes Insipidus
Familial Nephrogenic Diabetes Insipidus	Primary Nephrogenic Diabetes Insipidus

Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney Disease, Adult Type	Adpkd
Polycystic Kidney Diseases	Polycystic Kidney, Autosomal Dominant
Congenital Biliary Ectasias	Polycystic Kidney And Hepatic Disease 1
Polycystic Kidney Disease, Autosomal Dominant	Kidney, Polycystic, Disease, Autosomal Dominant
Adult Polycystic Kidney Disease	Polycystic Kidney, Adult Type
Apckd - [Autosomal Polycystic Kidney Disease]

Polycystic Kidney Disease

Polycystic Kidney Diseases	Pkd
Polycystic Renal Disease	Kidney Disease, Polycystic
Polycystic Kidney, Autosomal Dominant

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-110200	TC AQP1 1	Inhibitor	98.51%	Unkown
HY-RS00873	AQP11 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	AQP11	VGNC	VGNC:69866
Felis catus	AQP11	VGNC	VGNC:59860
Mus musculus	AQP11	MGD	MGI:1913583
Bos taurus	AQP11	VGNC	VGNC:26045
Rattus norvegicus	AQP11	RGD	RGD:628763
Canis familiaris	AQP11	VGNC	VGNC:38016

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