FAM177A1 - family with sequence similarity 177 member A1 Gene

Also Known as C14orf24

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 283635

About FAM177A1

Cytogenetic location: 14q13.2 Genomic coordinates (GRCh38): 14:35,044,907-35,083,383 (from NCBI)

This gene has 14 transcripts (splice variants), 265 orthologues and 1 paralogue. Ubiquitous expression in prostate (RPKM 15.8), colon (RPKM 14.8) and 25 other tissues.

Summary

This gene encodes a member of a conserved protein family. Alternative splicing results in multiple transcript variants. This gene is thought to be associated with susceptibility to juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]

FAM177A1 Products (3)

mRNA Protein Name
NM_001079519.1 NP_001072987.1 protein FAM177A1 isoform 2
NM_001289022.3 NP_001275951.1 protein FAM177A1 isoform 2
NM_173607.5 NP_775878.2 protein FAM177A1 isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAM177A1 Protein Structure

FAM177

FAM177: FAM177 family (37 - 156)

  • 0
  • 100
  • 200
  • 213 a.a.
Protein Preferred Names Protein Names

protein FAM177A1

Related Diseases

Diseases Alias
Myasthenic Syndrome, Congenital, 22

  • CMS22

  • Prepl Deficiency

  • Congenital Myasthenic Syndrome 22
Hypotonia-Cystinuria Syndrome

  • Cystinuria With Mitochondrial Disease

  • 2p21 Microdeletion Syndrome

  • HCS

  • Homozygous 2p16 Deletion Syndrome, Formerly

  • 2p21 Deletion Syndrome

  • Del(2)(P21)

  • Monosomy 2p21

  • Atypical Hypotonia-Cystinuria Syndrome

  • Atypical Hcs
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04699 FAM177A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FAM177A1 RGD RGD:2323636
Bos taurus FAM177A1 VGNC VGNC:50064
Mus musculus FAM177A1 MGD MGI:1920635
Felis catus FAM177A1 VGNC VGNC:104388
Canis familiaris FAM177A1 VGNC VGNC:49745