FIRRE - firre intergenic repeating RNA element Gene

Also Known as LINC01200

Species: Homo sapiens

Gene Type: ncRNA
Gene ID: 286467

About FIRRE

Cytogenetic location: Xq26.2 Genomic coordinates (GRCh38): X:131,691,525-131,830,643 (from NCBI)

This gene has 17 transcripts (splice variants). Low expression observed in reference dataset.

Summary

This gene produces a long RNA containing a repeating sequence. This RNA interacts with heterogeneous nuclear ribonucleoprotein U and coats chromosomes, where it plays an important role in the maintenance of repressive chromatin. This transcript can also act post-transcriptionally to regulate the stability of mRNAs during the innate immune response. [provided by RefSeq, Dec 2017]

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin-protein adaptor activity IPI
IPI: Inferred from physical interaction
24463464 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
24463464 GOA
Biological Process GO Annotation Evidence References Source
involved in chromatin organization IDA
IDA: Inferred from direct assay
24463464 GOA
Cellular Component GO Annotation Evidence References Source
located in Barr body IDA
IDA: Inferred from direct assay
24463464 GOA
located in X chromosome IDA
IDA: Inferred from direct assay
24463464 GOA
located in autosome IDA
IDA: Inferred from direct assay
24463464 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Diseases

Diseases Alias
Sotos Syndrome 1

  • Sotos1

  • Sotos Syndrome, Type 1

  • Sotos' Syndrome
Periventricular Nodular Heterotopia

  • Periventricular Heterotopia

  • Pvnh

  • Familial Nodular Heterotopia

  • Heterotopia, Periventricular

  • Periventricular Heterotopia, X-Linked
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus FIRRE MGD MGI:2147989