Rars1 - arginyl-tRNA synthetase 1 Gene

Also Known as Rars

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287191

Summary

Enables anion binding activity; arginine-tRNA Ligase activity; and tRNA binding activity. Involved in arginyl-tRNA aminoacylation. Part of Aminoacyl-tRNA Synthetase multienzyme complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 9. Orthologous to human RARS1 (arginyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Rars1 Products (1)

mRNA Protein Name
NM_001105777.2 NP_001099247.2 arginine--tRNA ligase, cytoplasmic

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
7082655 RGD
enables arginine binding IDA
IDA: Inferred from direct assay
7082655 RGD
enables arginine-tRNA ligase activity IDA
IDA: Inferred from direct assay
7082655 RGD
enables tRNA binding IDA
IDA: Inferred from direct assay
7082655 RGD
Biological Process GO Annotation Evidence References Source
involved in arginyl-tRNA aminoacylation IDA
IDA: Inferred from direct assay
7082655 RGD
Cellular Component GO Annotation Evidence References Source
part of aminoacyl-tRNA synthetase multienzyme complex IDA
IDA: Inferred from direct assay
7082655 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arginine--tRNA ligase, cytoplasmic

  • argRS

  • arginyl-tRNA synthetase, cytoplasmic

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11676 RARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rars1 NCBI NCBI:5917