Rars1 - arginyl-tRNA synthetase 1 Gene

Rattus norvegicus

Also known as Rars

Gene ID: 287191 | Gene type: protein coding

About Rars1

Summary

Enables anion binding activity; arginine-tRNA Ligase activity; and tRNA binding activity. Involved in arginyl-tRNA aminoacylation. Part of Aminoacyl-tRNA Synthetase multienzyme complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 9. Orthologous to human RARS1 (arginyl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Rars1 Products(1)

mRNA	Protein	Name
NM_001105777.2	NP_001099247.2	arginine--tRNA ligase, cytoplasmic

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ATP binding	IDA IDA: Inferred from direct assay	7082655	RGD
enables arginine binding	IDA IDA: Inferred from direct assay	7082655	RGD
enables arginine-tRNA ligase activity	IDA IDA: Inferred from direct assay	7082655	RGD
enables tRNA binding	IDA IDA: Inferred from direct assay	7082655	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in arginyl-tRNA aminoacylation	IDA IDA: Inferred from direct assay	7082655	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of aminoacyl-tRNA synthetase multienzyme complex	IDA IDA: Inferred from direct assay	7082655	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

arginine--tRNA ligase, cytoplasmic

argRS

arginyl-tRNA synthetase, cytoplasmic

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11676	RARS1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rars1	NCBI	NCBI:5917

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