Aloxe3 - arachidonate lipoxygenase 3 Gene

Also Known as eLOX-3; e-LOX-3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287424

Summary

Predicted to enable hepoxilin A3 synthase activity; intramolecular transferase activity, transferring hydroxy groups; and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. Involved in arachidonic acid metabolic process; hepoxilin biosynthetic process; and sensory perception of pain. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 1 and autosomal recessive congenital ichthyosis 3. Orthologous to human ALOXE3 (arachidonate Lipoxygenase 3). [provided by Alliance of Genome Resources, Apr 2022]

Aloxe3 Products (1)

mRNA Protein Name
NM_001105793.1 NP_001099263.1 hydroperoxide isomerase ALOXE3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in arachidonate metabolic process IDA
IDA: Inferred from direct assay
23382512 RGD
involved in hepoxilin biosynthetic process IDA
IDA: Inferred from direct assay
23382512 RGD
involved in sensory perception of pain IMP
IMP: Inferred from mutant phenotype
23382512 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hydroperoxide isomerase ALOXE3

  • epidermal LOX-3

  • epidermis-type lipoxygenase 3

  • hydroperoxy dehydratase ALOXE3

  • hydroperoxy icosatetraenoate dehydratase

  • hydroperoxy icosatetraenoate isomerase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00626 ALOXE3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aloxe3 NCBI NCBI:59344