2. Gene
  3. Vps53 - VPS53 subunit of GARP complex Gene

Vps53 - VPS53 subunit of GARP complex Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1311391

Gene ID: 287535 | Gene type: protein coding

About Vps53

Summary

Predicted to be involved in endocytic recycling and retrograde transport, endosome to Golgi. Predicted to act upstream of or within lysosomal transport. Predicted to be located in several cellular components, including Golgi apparatus; perinuclear region of cytoplasm; and recycling endosome. Predicted to be part of EARP complex and GARP complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2E. Orthologous to human VPS53 (VPS53 subunit of GARP complex). [provided by Alliance of Genome Resources, Apr 2022]

Vps53 Products(1)

mRNA Protein Name
NM_001105813.1 NP_001099283.1 vacuolar protein sorting-associated protein 53 homolog
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
27191843 RGD
Cellular Component GO Annotation Evidence Reference Source
located in recycling endosome IDA
IDA: Inferred from direct assay
25799061 RGD
located in trans-Golgi network IDA
IDA: Inferred from direct assay
25799061 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 53 homolog

VPS53 GARP complex subunit

vacuolar protein sorting 53 homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15698 VPS53 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps53 NCBI NCBI:55275