Vps53 - VPS53 subunit of GARP complex Gene

Also Known as RGD1311391

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287535

Summary

Predicted to be involved in endocytic recycling and retrograde transport, endosome to Golgi. Predicted to act upstream of or within lysosomal transport. Predicted to be located in several cellular components, including Golgi apparatus; perinuclear region of cytoplasm; and recycling endosome. Predicted to be part of EARP complex and GARP complex. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2E. Orthologous to human VPS53 (VPS53 subunit of GARP complex). [provided by Alliance of Genome Resources, Apr 2022]

Vps53 Products (1)

mRNA Protein Name
NM_001105813.1 NP_001099283.1 vacuolar protein sorting-associated protein 53 homolog

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
27191843 RGD
Cellular Component GO Annotation Evidence References Source
located in recycling endosome IDA
IDA: Inferred from direct assay
25799061 RGD
located in trans-Golgi network IDA
IDA: Inferred from direct assay
25799061 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 53 homolog

  • VPS53 GARP complex subunit

  • vacuolar protein sorting 53 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15698 VPS53 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps53 NCBI NCBI:55275