Mcoln1 - mucolipin TRP cation channel 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 288371

Summary

Enables NAADP-sensitive calcium-release channel activity. Involved in release of sequestered calcium ion into cytosol. Located in lysosomal membrane. Human ortholog(s) of this gene implicated in glycoproteinosis and mucolipidosis type IV. Orthologous to human MCOLN1 (mucolipin TRP cation channel 1). [provided by Alliance of Genome Resources, Apr 2022]

Mcoln1 Products (1)

mRNA Protein Name
NM_001105903.1 NP_001099373.1 mucolipin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables NAADP-sensitive calcium-release channel activity IDA
IDA: Inferred from direct assay
17613490 RGD
Biological Process GO Annotation Evidence References Source
involved in release of sequestered calcium ion into cytosol IDA
IDA: Inferred from direct assay
17613490 RGD
Cellular Component GO Annotation Evidence References Source
located in lysosomal membrane IDA
IDA: Inferred from direct assay
17613490 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucolipin-1

  • mucolipin 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS08244 MCOLN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20178 Mcoln1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26682 Mcoln1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mcoln1 NCBI NCBI:57192