Nudt15 - nudix hydrolase 15 Gene

Rattus norvegicus

Gene ID: 290365 | Gene type: protein coding

About Nudt15

Summary

Predicted to enable 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity; 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity; and nucleoside-diphosphatase activity. Predicted to be involved in several processes, including DNA protection; dGTP catabolic process; and regulation of proteasomal protein catabolic process. Predicted to act upstream of or within purine deoxyribonucleoside triphosphate catabolic process and response to Reactive Oxygen Species. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in thiopurine S-methyltransferase deficiency. Orthologous to human NUDT15 (nudix hydrolase 15). [provided by Alliance of Genome Resources, Apr 2022]

Nudt15 Products(1)

mRNA	Protein	Name
NM_001106049.2	NP_001099519.1	nucleotide triphosphate diphosphatase NUDT15

Protein Preferred Names

Protein Names

nucleotide triphosphate diphosphatase NUDT15

nudix (nucleoside diphosphate linked moiety X)-type motif 15	probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15
probable 8-oxo-dGTP diphosphatase NUDT15

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-139193	TH1760	Inhibitor	/	Unkown
HY-RS09665	NUDT15 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nudt15	NCBI	NCBI:55270

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