2. Gene
  3. Uqcrfs1 - ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 Gene

Uqcrfs1 - ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as LRRGT00195

Gene ID: 291103 | Gene type: protein coding

About Uqcrfs1

Summary

Predicted to enable oxidoreductase activity. Involved in response to antibiotic; response to hormone; and response to xenobiotic stimulus. Located in mitochondrial membrane. Part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Orthologous to several human genes including UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1). [provided by Alliance of Genome Resources, Apr 2022]

Uqcrfs1 Products(1)

mRNA Protein Name
NM_001008888.1 NP_001008888.1 cytochrome b-c1 complex subunit Rieske, mitochondrial
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
19166612 RGD
Biological Process GO Annotation Evidence Reference Source
involved in response to hormone IEP
IEP: Inferred from expression pattern
2776768 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
15730530 RGD
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
16023995 RGD
part of respiratory chain complex III IDA
IDA: Inferred from direct assay
12794875 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome b-c1 complex subunit Rieske, mitochondrial

RISP

Rieske protein UQCRFS1

complex III subunit 5

cytochrome b-c1 complex subunit 5

liver regeneration-related protein LRRGT00195

rieske iron-sulfur protein

ubiquinol-cytochrome c reductase iron-sulfur subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15501 UQCRFS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uqcrfs1 NCBI NCBI:7386