Dcdc2 - doublecortin domain containing 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 291130

Summary

This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Knockdown of this gene expression results in neuronal migration disorders similar to those seen in the brains of dyslexics. [provided by RefSeq, Sep 2010]

Dcdc2 Products (1)

mRNA Protein Name
NM_001106110.2 NP_001099580.2 doublecortin domain-containing protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables kinesin binding IPI
IPI: Inferred from physical interaction
21698230 RGD
Biological Process GO Annotation Evidence References Source
involved in neuron migration IMP
IMP: Inferred from mutant phenotype
16278297 RGD
Cellular Component GO Annotation Evidence References Source
located in kinocilium IDA
IDA: Inferred from direct assay
25601850 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

doublecortin domain-containing protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03574 DCDC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dcdc2 NCBI NCBI:51473