Dcdc2 - doublecortin domain containing 2 Gene

Rattus norvegicus

Gene ID: 291130 | Gene type: protein coding

About Dcdc2

Summary

This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Knockdown of this gene expression results in neuronal migration disorders similar to those seen in the brains of dyslexics. [provided by RefSeq, Sep 2010]

Dcdc2 Products(1)

mRNA	Protein	Name
NM_001106110.2	NP_001099580.2	doublecortin domain-containing protein 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables kinesin binding	IPI IPI: Inferred from physical interaction	21698230	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in neuron migration	IMP IMP: Inferred from mutant phenotype	16278297	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in kinocilium	IDA IDA: Inferred from direct assay	25601850	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

doublecortin domain-containing protein 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03574	DCDC2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dcdc2	NCBI	NCBI:51473

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