Fbh1 - F-box DNA helicase 1 Gene

Predicted to enable ATP-dependent activity, acting on DNA and DNA binding activity. Predicted to be involved in several processes, including DNA metabolic process; negative regulation of double-strand break repair via homologous recombination; and protein ubiquitination. Predicted to act upstream of or within several processes, including DNA catabolic process, endonucleolytic; positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage; and response to intra-S DNA damage checkpoint signaling. Predicted to be located in chromatin and nucleus. Predicted to be part of SCF ubiquitin Ligase complex. Orthologous to human FBH1 (F-box DNA helicase 1). [provided by Alliance of Genome Resources, Apr 2022]