Aqp8 - aquaporin 8 Gene

Also Known as AQP-8

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29172

Summary

Enables water channel activity. Involved in canalicular bile acid transport and water transport. Located in intracellular canaliculus and intracellular membrane-bounded organelle. Biomarker of brain ischemia. Orthologous to human AQP8 (Aquaporin 8). [provided by Alliance of Genome Resources, Apr 2022]

Aqp8 Products (1)

mRNA Protein Name
NM_019158.2 NP_062031.1 aquaporin-8

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ammonium channel activity IDA
IDA: Inferred from direct assay
15988592 RGD
enables methylammonium channel activity IDA
IDA: Inferred from direct assay
15948717 RGD
enables water channel activity IDA
IDA: Inferred from direct assay
11932260 RGD
enables water channel activity IMP
IMP: Inferred from mutant phenotype
16624991 RGD
Biological Process GO Annotation Evidence References Source
involved in ammonium import across plasma membrane IDA
IDA: Inferred from direct assay
16624991 RGD
involved in ammonium transmembrane transport IDA
IDA: Inferred from direct assay
15988592 RGD
involved in canalicular bile acid transport IDA
IDA: Inferred from direct assay
11932260 RGD
involved in hydrogen peroxide transmembrane transport IMP
IMP: Inferred from mutant phenotype
31372390 RGD
involved in methylammonium transmembrane transport IMP
IMP: Inferred from mutant phenotype
23299935 RGD
involved in methylammonium transport IDA
IDA: Inferred from direct assay
15948717 RGD
involved in transepithelial water transport IDA
IDA: Inferred from direct assay
16177191 RGD
involved in water transport IDA
IDA: Inferred from direct assay
11932260 RGD
involved in water transport IMP
IMP: Inferred from mutant phenotype
16624991 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
11436986 RGD
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
11205061 RGD
located in brush border membrane IDA
IDA: Inferred from direct assay
18059526 RGD
located in intracellular canaliculus IDA
IDA: Inferred from direct assay
11436986 RGD
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
15749715 RGD
located in mitochondrial membrane IDA
IDA: Inferred from direct assay
33892285 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
33892285 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aquaporin-8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00880 AQP8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aqp8 NCBI NCBI:343