2. Gene
  3. Sprtn - SprT-like N-terminal domain Gene

Sprtn - SprT-like N-terminal domain Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1559496

Gene ID: 292101 | Gene type: protein coding

About Sprtn

Summary

Predicted to enable several functions, including DNA binding activity; K63-linked polyubiquitin modification-dependent protein binding activity; and metalloendopeptidase activity. Predicted to be involved in several processes, including DNA repair; positive regulation of protein ubiquitination; and protein autoprocessing. Predicted to be located in chromatin and nuclear speck. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Ruijs-Aalfs syndrome. Orthologous to human SPRTN (SprT-like N-terminal domain). [provided by Alliance of Genome Resources, Apr 2022]

Sprtn Products(1)

mRNA Protein Name
NM_001399182.1 NP_001386111.1 DNA-dependent metalloprotease SPRTN
Protein Preferred Names Protein Names

DNA-dependent metalloprotease SPRTN

protein with SprT-like domain at the N terminus

spartan

sprT-like domain-containing protein Spartan

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13720 SPRTN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sprtn NCBI NCBI:83932