Akap13 - A-kinase anchoring protein 13 Gene

Rattus norvegicus

Also known as AKAP-13; AKAP-Lbc

Gene ID: 293024 | Gene type: protein coding

About Akap13

Summary

Enables MAP-kinase scaffold activity. Involved in several processes, including Adrenergic Receptor signaling pathway; cell growth involved in cardiac muscle cell development; and positive regulation of intracellular signal transduction. Located in perinuclear region of cytoplasm. Orthologous to human AKAP13 (A-kinase anchoring protein 13). [provided by Alliance of Genome Resources, Apr 2022]

Akap13 Products(1)

mRNA	Protein	Name
NM_001106271.3	NP_001099741.2	A-kinase anchor protein 13

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables MAP-kinase scaffold activity	IMP IMP: Inferred from mutant phenotype	23716597	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in G protein-coupled receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	20139090	RGD
involved in adrenergic receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	23090968	RGD
involved in cell growth involved in cardiac muscle cell development	IMP IMP: Inferred from mutant phenotype	18951085	RGD
involved in nuclear export	IMP IMP: Inferred from mutant phenotype	18951085	RGD
involved in positive regulation of MAP kinase activity	IMP IMP: Inferred from mutant phenotype	23716597	RGD
involved in positive regulation of canonical NF-kappaB signal transduction	IMP IMP: Inferred from mutant phenotype	23090968	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	18951085	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

A-kinase anchor protein 13

A kinase (PRKA) anchor protein 13

protein kinase A anchoring protein Rt31

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00516	AKAP13 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Akap13	NCBI	NCBI:11214

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