Best1 - bestrophin 1 Gene

Also known as Vmd2

About Best1

Summary

Predicted to enable identical protein binding activity. Predicted to contribute to Chloride Channel activity. Predicted to be involved in transepithelial chloride transport. Predicted to act upstream of or within chloride transport; detection of light stimulus involved in visual perception; and regulation of calcium ion transport. Predicted to be located in basolateral plasma membrane. Predicted to be part of Chloride Channel complex. Human ortholog(s) of this gene implicated in autosomal dominant vitreoretinochoroidopathy; bestrophinopathy; macular degeneration; retinitis pigmentosa 50; and vitelliform macular dystrophy. Orthologous to human BEST1 (bestrophin 1). [provided by Alliance of Genome Resources, Apr 2022]