Dnah5 - dynein, axonemal, heavy chain 5 Gene

Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in flagellated sperm motility and outer dynein arm assembly. Predicted to act upstream of or within several processes, including determination of left/right symmetry; epithelial cilium movement involved in extracellular fluid movement; and lateral ventricle development. Predicted to be located in 9+2 motile cilium and cytoplasm. Predicted to be part of outer dynein arm. Predicted to be active in axoneme and motile cilium. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 3. Orthologous to human DNAH5 (dynein axonemal heavy chain 5). [provided by Alliance of Genome Resources, Apr 2022]