Hsd17b7 - hydroxysteroid (17-beta) dehydrogenase 7 Gene

Rattus norvegicus

Gene ID: 29540 | Gene type: protein coding

About Hsd17b7

Summary

Enables estradiol 17-beta-dehydrogenase activity and Prolactin receptor binding activity. Involved in several processes, including estrogen biosynthetic process; response to estradiol; and response to Prolactin. Located in membrane. Biomarker of polycystic ovary syndrome. Orthologous to human HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7). [provided by Alliance of Genome Resources, Apr 2022]

Hsd17b7 Products(1)

mRNA	Protein	Name
NM_017235.3	NP_058931.1	3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity	IDA IDA: Inferred from direct assay	9658408	RGD
enables prolactin receptor binding	IPI IPI: Inferred from physical interaction	8663045	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in estrogen biosynthetic process	IDA IDA: Inferred from direct assay	9658408	RGD
involved in hippocampus development	IEP IEP: Inferred from expression pattern	21047951	RGD
involved in maternal process involved in female pregnancy	IEP IEP: Inferred from expression pattern	9231770	RGD
involved in response to estradiol	IEP IEP: Inferred from expression pattern	9231770	RGD
involved in response to organic cyclic compound	IEP IEP: Inferred from expression pattern	19527300	RGD
involved in response to prolactin	IEP IEP: Inferred from expression pattern	9231770	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	9231770	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

17-beta-HSD 7	17-beta-hydroxysteroid dehydrogenase 7
3-keto-steroid reductase	PRAP
PRL receptor-associated protein	dihydrotestosterone oxidoreductase
estradiol 17-beta-dehydrogenase 7	hydroxysteroid dehydrogenase 17 beta, type 7
prolactin receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06399	HSD17B7 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W749520	Zymosterone		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hsd17b7	NCBI	NCBI:51478

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