Hsd17b7 - hydroxysteroid (17-beta) dehydrogenase 7 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29540

Summary

Enables estradiol 17-beta-dehydrogenase activity and Prolactin receptor binding activity. Involved in several processes, including estrogen biosynthetic process; response to estradiol; and response to Prolactin. Located in membrane. Biomarker of polycystic ovary syndrome. Orthologous to human HSD17B7 (hydroxysteroid 17-beta dehydrogenase 7). [provided by Alliance of Genome Resources, Apr 2022]

Hsd17b7 Products (1)

mRNA Protein Name
NM_017235.3 NP_058931.1 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity IDA
IDA: Inferred from direct assay
9658408 RGD
enables prolactin receptor binding IPI
IPI: Inferred from physical interaction
8663045 RGD
Biological Process GO Annotation Evidence References Source
involved in estrogen biosynthetic process IDA
IDA: Inferred from direct assay
9658408 RGD
involved in hippocampus development IEP
IEP: Inferred from expression pattern
21047951 RGD
involved in maternal process involved in female pregnancy IEP
IEP: Inferred from expression pattern
9231770 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
9231770 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
19527300 RGD
involved in response to prolactin IEP
IEP: Inferred from expression pattern
9231770 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
9231770 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

  • 17-beta-HSD 7

  • 17-beta-hydroxysteroid dehydrogenase 7

  • 3-keto-steroid reductase

  • PRAP

  • PRL receptor-associated protein

  • dihydrotestosterone oxidoreductase

  • estradiol 17-beta-dehydrogenase 7

  • hydroxysteroid dehydrogenase 17 beta, type 7

  • prolactin receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06399 HSD17B7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W749520 Zymosterone / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hsd17b7 NCBI NCBI:51478