2. Gene
  3. Gjb1 - gap junction protein, beta 1 Gene

Gjb1 - gap junction protein, beta 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Cx32; Cxng

Gene ID: 29584 | Gene type: protein coding

About Gjb1

Summary

Enables gap junction channel activity. Involved in epididymis development and purine ribonucleotide transport. Located in gap junction and lateral plasma membrane. Part of protein-containing complex. Biomarker of autoimmune thyroiditis and extrahepatic cholestasis. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease X-linked dominant 1. Orthologous to human GJB1 (Gap Junction Protein beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Gjb1 Products(1)

mRNA Protein Name
NM_017251.2 NP_058947.1 gap junction beta-1 protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables gap junction channel activity IDA
IDA: Inferred from direct assay
12119284 RGD
Biological Process GO Annotation Evidence Reference Source
involved in epididymis development IEP
IEP: Inferred from expression pattern
12388089 RGD
involved in purine ribonucleotide transport IDA
IDA: Inferred from direct assay
12119284 RGD
Cellular Component GO Annotation Evidence Reference Source
located in gap junction IDA
IDA: Inferred from direct assay
12119284 RGD
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
12388089 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
15817491 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction beta-1 protein

GAP junction 28 kDa liver protein

connexin g

connexin-32

gap junction membrane channel protein beta 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05446 GJB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gjb1 NCBI NCBI:2705