Vps16 - VPS16 core subunit of CORVET and HOPS complexes Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 296159

Summary

Enables actin filament binding activity. Predicted to be involved in several processes, including autophagosome maturation; endosome to lysosome transport; and vacuole fusion, non-autophagic. Predicted to act upstream of or within viral entry into host cell. Located in axon; endosome; and neuronal cell body. Human ortholog(s) of this gene implicated in dystonia. Orthologous to human VPS16 (VPS16 core subunit of CORVET and HOPS complexes). [provided by Alliance of Genome Resources, Apr 2022]

Vps16 Products (1)

mRNA Protein Name
NM_001005541.1 NP_001005541.1 vacuolar protein sorting-associated protein 16 homolog

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin filament binding IDA
IDA: Inferred from direct assay
14668490 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14668490 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
14732470 RGD
located in endosome IDA
IDA: Inferred from direct assay
14668490 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
14732470 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
17027648 RGD
is active in presynapse IMP
IMP: Inferred from mutant phenotype
17027648 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 16 homolog

  • VPS16 CORVET/HOPS core subunit

  • vacuolar protein sorting 16 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15676 VPS16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps16 NCBI NCBI:64601