2. Gene
  3. Pmpca - peptidase, mitochondrial processing subunit alpha Gene

Pmpca - peptidase, mitochondrial processing subunit alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 296588 | Gene type: protein coding

About Pmpca

Summary

Enables endopeptidase activity. Contributes to metallopeptidase activity. Involved in proteolysis. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 2. Orthologous to human PMPCA (peptidase, mitochondrial processing subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Pmpca Products(1)

mRNA Protein Name
NM_001003673.1 NP_001003673.1 mitochondrial-processing peptidase subunit alpha
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
2236012 RGD
contributes to metallopeptidase activity IDA
IDA: Inferred from direct assay
7490252 RGD
Biological Process GO Annotation Evidence Reference Source
involved in protein processing IDA
IDA: Inferred from direct assay
2236012 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial-processing peptidase subunit alpha

P-55

alpha-MPP

inactive zinc metalloprotease alpha

mitochondrial processing peptidase alpha subunit, mitochondrial

peptidase (mitochondrial processing) alpha

peptidase, mitochondrial processing alpha subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10770 PMPCA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmpca NCBI NCBI:23203