Pmpca - peptidase, mitochondrial processing subunit alpha Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 296588

Summary

Enables endopeptidase activity. Contributes to metallopeptidase activity. Involved in proteolysis. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 2. Orthologous to human PMPCA (peptidase, mitochondrial processing subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Pmpca Products (1)

mRNA Protein Name
NM_001003673.1 NP_001003673.1 mitochondrial-processing peptidase subunit alpha

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables endopeptidase activity IDA
IDA: Inferred from direct assay
2236012 RGD
contributes to metallopeptidase activity IDA
IDA: Inferred from direct assay
7490252 RGD
Biological Process GO Annotation Evidence References Source
involved in protein processing IDA
IDA: Inferred from direct assay
2236012 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitochondrial-processing peptidase subunit alpha

  • P-55

  • alpha-MPP

  • inactive zinc metalloprotease alpha

  • mitochondrial processing peptidase alpha subunit, mitochondrial

  • peptidase (mitochondrial processing) alpha

  • peptidase, mitochondrial processing alpha subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10770 PMPCA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmpca NCBI NCBI:23203