Cacna1g - calcium voltage-gated channel subunit alpha1 G Gene

Rattus norvegicus

Gene ID: 29717 | Gene type: protein coding

About Cacna1g

Summary

Enables low voltage-gated Calcium Channel activity. Involved in several processes, including artery smooth muscle contraction; calcium ion transport; and cellular response to dexamethasone stimulus. Located in several cellular components, including dendrite; neuronal cell body; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in cerebellar ataxia type 42. Orthologous to human CACNA1G (calcium voltage-gated channel subunit alpha1 G). [provided by Alliance of Genome Resources, Apr 2022]

Cacna1g Products(2)

mRNA	Protein	Name
NM_001308302.2	NP_001295231.2	voltage-dependent T-type calcium channel subunit alpha-1G isoform 1
NM_031601.5	NP_113789.4	voltage-dependent T-type calcium channel subunit alpha-1G isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables low voltage-gated calcium channel activity	IDA IDA: Inferred from direct assay	16935432	RGD
enables voltage-gated calcium channel activity	IDA IDA: Inferred from direct assay	9495342	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in artery smooth muscle contraction	IMP IMP: Inferred from mutant phenotype	18759855	RGD
involved in calcium ion import	IDA IDA: Inferred from direct assay	16935432	RGD
involved in calcium ion transport into cytosol	IDA IDA: Inferred from direct assay	18760992	RGD
involved in cellular response to dexamethasone stimulus	IEP IEP: Inferred from expression pattern	18820838	RGD
involved in positive regulation of calcium ion-dependent exocytosis	IMP IMP: Inferred from mutant phenotype	17172292	RGD
involved in positive regulation of cytosolic calcium ion concentration	IMP IMP: Inferred from mutant phenotype	11577029	RGD
involved in regulation of calcium ion transport	IMP IMP: Inferred from mutant phenotype	17172292	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in cell body	IDA IDA: Inferred from direct assay	10400082	RGD
located in dendrite	IDA IDA: Inferred from direct assay	17100846	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	17100846	RGD
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	18759855	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

voltage-dependent T-type calcium channel subunit alpha-1G

calcium channel, voltage-dependent, T type, alpha 1G subunit

voltage-gated calcium channel subunit alpha Cav3.1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01797	CACNA1G Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cacna1g	NCBI	NCBI:8913

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