Cacna1g - calcium voltage-gated channel subunit alpha1 G Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29717

Summary

Enables low voltage-gated Calcium Channel activity. Involved in several processes, including artery smooth muscle contraction; calcium ion transport; and cellular response to dexamethasone stimulus. Located in several cellular components, including dendrite; neuronal cell body; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in cerebellar ataxia type 42. Orthologous to human CACNA1G (calcium voltage-gated channel subunit alpha1 G). [provided by Alliance of Genome Resources, Apr 2022]

Cacna1g Products (2)

mRNA Protein Name
NM_001308302.2 NP_001295231.2 voltage-dependent T-type calcium channel subunit alpha-1G isoform 1
NM_031601.5 NP_113789.4 voltage-dependent T-type calcium channel subunit alpha-1G isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables low voltage-gated calcium channel activity IDA
IDA: Inferred from direct assay
16935432 RGD
enables voltage-gated calcium channel activity IDA
IDA: Inferred from direct assay
9495342 RGD
Biological Process GO Annotation Evidence References Source
involved in artery smooth muscle contraction IMP
IMP: Inferred from mutant phenotype
18759855 RGD
involved in calcium ion import IDA
IDA: Inferred from direct assay
16935432 RGD
involved in calcium ion transport into cytosol IDA
IDA: Inferred from direct assay
18760992 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: Inferred from expression pattern
18820838 RGD
involved in positive regulation of calcium ion-dependent exocytosis IMP
IMP: Inferred from mutant phenotype
17172292 RGD
involved in positive regulation of cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
11577029 RGD
involved in regulation of calcium ion transport IMP
IMP: Inferred from mutant phenotype
17172292 RGD
Cellular Component GO Annotation Evidence References Source
located in cell body IDA
IDA: Inferred from direct assay
10400082 RGD
located in dendrite IDA
IDA: Inferred from direct assay
17100846 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
17100846 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
18759855 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent T-type calcium channel subunit alpha-1G

  • calcium channel, voltage-dependent, T type, alpha 1G subunit

  • voltage-gated calcium channel subunit alpha Cav3.1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01797 CACNA1G Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacna1g NCBI NCBI:8913