Atp6v1e1 - ATPase H+ transporting V1 subunit E1 Gene

Rattus norvegicus

Also known as P31; Vma4; Atp6e; Atp6e2

Gene ID: 297566 | Gene type: protein coding

About Atp6v1e1

Summary

Predicted to enable ATPase binding activity and proton-transporting ATPase activity, rotational mechanism. Predicted to act upstream of or within proton transmembrane transport. Part of vacuolar proton-transporting V-type ATPase, V1 domain. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIC. Orthologous to human ATP6V1E1 (ATPase H+ transporting V1 subunit E1). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v1e1 Products(1)

mRNA	Protein	Name
NM_198745.3	NP_942040.2	V-type proton ATPase subunit E 1

Gene Ontology

Cellular Component

Cellular Component GO Annotation	Evidence	Reference	Source
is active in extrinsic component of synaptic vesicle membrane	EXP EXP: Inferred from Experiment	32165585	RGD
is active in extrinsic component of synaptic vesicle membrane	IDA IDA: Inferred from direct assay	32165585	RGD
part of vacuolar proton-transporting V-type ATPase, V1 domain	IDA IDA: Inferred from direct assay	32165585	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

V-type proton ATPase subunit E 1

ATPase, H+ transporting, V1 subunit E	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E
ATPase, H+ transporting, lysosomal V1 subunit E1	V-ATPase subunit E 1
VATPase, H+ transporting, lysosomal V1 subunit E1	vacuolar H(+)-ATPase, E subunit
vacu

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01229	ATP6V1E1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Atp6v1e1	NCBI	NCBI:529

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