UQCR10 - ubiquinol-cytochrome c reductase, complex III subunit X Gene

Also Known as QCR9; UCRC; HSPC051; HSPC119; HSPC151; UCCR7.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29796

About UQCR10

Cytogenetic location: 22q12.2 Genomic coordinates (GRCh38): 22:29,767,369-29,770,413 (from NCBI)

This gene has 2 transcripts (splice variants) and 171 orthologues. Ubiquitous expression in heart (RPKM 65.5), colon (RPKM 45.4) and 25 other tissues.

Summary

UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase; EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).[supplied by OMIM, Mar 2008]

UQCR10 Products (2)

mRNA Protein Name
NM_001003684.2 NP_001003684.1 cytochrome b-c1 complex subunit 9 isoform b
NM_013387.4 NP_037519.2 cytochrome b-c1 complex subunit 9 isoform a

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
35101990 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
28844695 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

UQCR10 Protein Structure

UCR_UQCRX_QCR9

UCR_UQCRX_QCR9: Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like (8 - 61)

  • 0
  • 63 a.a.
Protein Preferred Names Protein Names

cytochrome b-c1 complex subunit 9

  • cytochrome C1, nonheme 7kDa protein

Related Diseases

Diseases Alias
Mitochondrial Complex Iii Deficiency

  • Complex 3 Mitochondrial Respiratory Chain Deficiency

  • Isolated Coq-Cytochrome C Reductase Deficiency

  • Ubiquinone-Cytochrome C Oxidoreductase Deficiency
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15496 UQCR10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus UQCR10 MGD MGI:1913402
Rattus norvegicus UQCR10 RGD RGD:1595126
Felis catus UQCR10 VGNC VGNC:80544
Bos taurus UQCR10 VGNC VGNC:36693
Canis familiaris UQCR10 VGNC VGNC:48162