2. Gene
  3. Rnaseh1 - ribonuclease H1 Gene

Rnaseh1 - ribonuclease H1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 298933 | Gene type: protein coding

About Rnaseh1

Summary

This gene encodes an Endonuclease that specifically degrades the RNA of RNA-DNA hybrids and is necessary for DNA replication and repair. This enzyme is present in both mitochondria and nuclei, which are resulted from translation of a single mRNA with two in-frame initiation start codons. The use of the first start codon produces the mitochondrial isoform and the use of the second start codon produces the nuclear isoform. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF) which encodes 7aa in rat. [provided by RefSeq, Nov 2013]

Rnaseh1 Products(2)

mRNA Protein Name
NM_001013097.2 NP_001013115.1 ribonuclease H1 isoform 1 precursor
NM_001286938.1 NP_001273867.1 ribonuclease H1 isoform 2
Protein Preferred Names Protein Names

ribonuclease H1

RNase H1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12024 RNASEH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rnaseh1 NCBI NCBI:246243