Abhd17a - abhydrolase domain containing 17A, depalmitoylase Gene

Also Known as Fam108a; upf0227; Fam108a1; RGD1359682

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 299617

Summary

Enables palmitoyl-(protein) hydrolase activity. Involved in several processes, including negative regulation of protein localization to microtubule; positive regulation of protein localization to endosome; and protein depalmitoylation. Located in plasma membrane; postsynaptic density; and recycling endosome membrane. Is active in glutamatergic synapse. Is anchored component of postsynaptic density membrane and anchored component of postsynaptic recycling endosome membrane. Orthologous to human ABHD17A (abhydrolase domain containing 17A, depalmitoylase). [provided by Alliance of Genome Resources, Apr 2022]

Abhd17a Products (1)

mRNA Protein Name
NM_001006983.1 NP_001006984.1 alpha/beta hydrolase domain-containing protein 17A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables palmitoyl-(protein) hydrolase activity IDA
IDA: Inferred from direct assay
27307232 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of protein localization to microtubule IMP
IMP: Inferred from mutant phenotype
28521134 RGD
involved in positive regulation of protein localization to endosome IMP
IMP: Inferred from mutant phenotype
28521134 RGD
involved in protein depalmitoylation IDA
IDA: Inferred from direct assay
27307232 RGD
involved in regulation of postsynapse organization IDA
IDA: Inferred from direct assay
27307232 RGD
involved in regulation of postsynapse organization IEP
IEP: Inferred from expression pattern
27307232 RGD
involved in regulation of postsynapse organization IMP
IMP: Inferred from mutant phenotype
27307232 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
27307232 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
27307232 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
27307232 RGD
located in postsynaptic density IDA
IDA: Inferred from direct assay
27307232 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
27307232 RGD
is active in postsynaptic density membrane IMP
IMP: Inferred from mutant phenotype
27307232 RGD
is active in postsynaptic recycling endosome membrane IDA
IDA: Inferred from direct assay
27307232 RGD
is active in postsynaptic recycling endosome membrane IMP
IMP: Inferred from mutant phenotype
27307232 RGD
located in recycling endosome membrane IDA
IDA: Inferred from direct assay
27307232 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha/beta hydrolase domain-containing protein 17A

  • abhydrolase domain-containing protein 17A

  • abhydrolase domain-containing protein FAM108A

  • family with sequence similarity 108, member A1

  • protein ABHD17A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00091 ABHD17A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abhd17a NCBI NCBI:81926