OBP2A - odorant binding protein 2A Gene
Also Known as OBP; LCN13; OBP2C; OBPIIa; hOBPIIa
Species: Homo sapiens
About OBP2A
This gene has 7 transcripts (splice variants), 191 orthologues and 12 paralogues. Biased expression in testis (RPKM 2.5), skin (RPKM 0.2) and 1 other tissue.
Summary
This gene encodes a small extracellular protein belonging to the lipocalin superfamily. The protein is thought to transport small, hydrophobic, volatile molecules or odorants through the nasal mucus to olfactory receptors, and may also function as a scavenger of highly concentrated or toxic odors. The protein is expressed as a monomer in the nasal mucus, and can bind diverse types of odorants with a higher affinity for aldehydes and fatty acids. This gene and a highly similar family member are located in a cluster of lipocalin genes on chromosome 9. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
OBP2A Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001293189.2 | NP_001280118.1 | odorant-binding protein 2a isoform gamma precursor |
| NM_001293193.2 | NP_001280122.1 | odorant-binding protein 2a isoform delta precursor |
| NM_001412135.1 | NP_001399064.1 | odorant-binding protein 2a isoform 5 precursor |
| NM_014582.3 | NP_055397.1 | odorant-binding protein 2a isoform alpha precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables odorant binding |
IDA
IDA: Inferred from direct assay
|
16546182 | GOA |
OBP2A Protein Structure
Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (26 - 163)
- 0
- 100
- 170 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
odorant-binding protein 2a |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Trombiculiasis |
|
|
| Syringomyelia |
|
|
| Vaginal Discharge |
|