2. Gene
  3. Lca5 - lebercilin LCA5 Gene

Lca5 - lebercilin LCA5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1308555

Gene ID: 300866 | Gene type: protein coding

About Lca5

Summary

Predicted to be involved in intraciliary transport. Predicted to act upstream of or within photoreceptor cell maintenance. Located in ciliary basal body and photoreceptor connecting cilium. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 5. Orthologous to human LCA5 (lebercilin LCA5). [provided by Alliance of Genome Resources, Apr 2022]

Lca5 Products(1)

mRNA Protein Name
NM_001393917.1 NP_001380846.1 lebercilin
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in ciliary basal body IDA
IDA: Inferred from direct assay
17546029 RGD
located in photoreceptor connecting cilium IDA
IDA: Inferred from direct assay
17546029 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lebercilin

LCA5, lebercilin

leber congenital amaurosis 5 protein homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07548 LCA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-177795 5β-Cholanic acid-3,6-dione / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lca5 NCBI NCBI:167691