2. Gene
  3. Ercc5 - ERCC excision repair 5, endonuclease Gene

Ercc5 - ERCC excision repair 5, endonuclease Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Xpg

Gene ID: 301382 | Gene type: protein coding

About Ercc5

Summary

Predicted to enable several functions, including DNA binding activity; RNA polymerase II complex binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including DNA repair; negative regulation of apoptotic process; and response to UV-C. Predicted to act upstream of or within UV protection; determination of adult lifespan; and nucleotide-excision repair. Predicted to be part of nucleotide-excision repair complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in cerebrooculofacioskeletal syndrome 3; melanoma; and xeroderma pigmentosum group G. Orthologous to human ERCC5 (ERCC excision repair 5, Endonuclease). [provided by Alliance of Genome Resources, Apr 2022]

Ercc5 Products(6)

mRNA Protein Name
XM_039084554.1 XP_038940482.1 DNA repair protein complementing XP-G cells isoform X1
XM_017596799.2 XP_017452288.2 DNA repair protein complementing XP-G cells isoform X4
XM_017596798.2 XP_017452287.2 DNA repair protein complementing XP-G cells isoform X4
XM_017596800.2 XP_017452289.2 DNA repair protein complementing XP-G cells isoform X5
XM_039084556.1 XP_038940484.1 DNA repair protein complementing XP-G cells isoform X3
XM_039084555.1 XP_038940483.1 DNA repair protein complementing XP-G cells isoform X2
Protein Preferred Names Protein Names

DNA repair protein complementing XP-G cells

ERCC excision repair 5, endonuclease

excision repair cross-complementation group 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04482 ERCC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ercc5 NCBI NCBI:2073