Gpr143 - G protein-coupled receptor 143 Gene

Predicted to enable L-DOPA receptor activity; amino acid binding activity; and dopamine binding activity. Predicted to be involved in several processes, including intracellular signal transduction; melanosome organization; and melanosome transport. Predicted to be located in several cellular components, including apical plasma membrane; lysosomal membrane; and melanosome. Predicted to be active in melanosome membrane and plasma membrane. Human ortholog(s) of this gene implicated in congenital nystagmus 6. Orthologous to human GPR143 (G protein-coupled receptor 143). [provided by Alliance of Genome Resources, Apr 2022]