Frmpd4 - FERM and PDZ domain containing 4 Gene

Rattus norvegicus

Also known as RGD1566031

Gene ID: 302656 | Gene type: protein coding

About Frmpd4

Summary

Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Involved in postsynaptic actin Cytoskeleton organization. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 104. Orthologous to human FRMPD4 (FERM and PDZ domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]

Frmpd4 Products(1)

mRNA	Protein	Name
NM_001106960.1	NP_001100430.1	FERM and PDZ domain-containing protein 4

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in postsynaptic actin cytoskeleton organization	IDA IDA: Inferred from direct assay	19118189	RGD
involved in postsynaptic actin cytoskeleton organization	IMP IMP: Inferred from mutant phenotype	19118189	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	19118189	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	19118189	RGD
is active in postsynaptic density	IDA IDA: Inferred from direct assay	19118189	RGD
is active in postsynaptic density	IMP IMP: Inferred from mutant phenotype	19118189	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

FERM and PDZ domain-containing protein 4

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05109	FRMPD4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Frmpd4	NCBI	NCBI:9758

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