Slx4 - SLX4 structure-specific endonuclease subunit Gene

Rattus norvegicus

Also known as Btbd12; RGD1566009

Gene ID: 302953 | Gene type: protein coding

About Slx4

Summary

Predicted to enable enzyme activator activity and enzyme binding activity. Predicted to contribute to 3'-flap Endonuclease activity; 5'-flap Endonuclease activity; and crossover junction endodeoxyribonuclease activity. Predicted to be involved in DNA metabolic process and regulation of telomere maintenance. Predicted to act upstream of or within response to intra-S DNA damage checkpoint signaling. Predicted to be located in cell junction; cytosol; and nucleoplasm. Predicted to be part of Slx1-Slx4 complex. Predicted to colocalize with chromatin and chromosome, telomeric region. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group P. Orthologous to human SLX4 (SLX4 structure-specific Endonuclease subunit). [provided by Alliance of Genome Resources, Apr 2022]

Slx4 Products(1)

mRNA	Protein	Name
NM_001398651.1	NP_001385580.1	SLX4 structure-specific endonuclease subunit

Protein Preferred Names

Protein Names

SLX4 structure-specific endonuclease subunit

structure-specific endonuclease subunit SLX4

BTB (POZ) domain containing 12

SLX4 structure-specific endonuclease subunit homolog

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13389	SLX4 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13390	SLX4IP Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slx4	NCBI	NCBI:84464

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